Publications
Shukla A, Rodriguez S, Brennan-Krohn T. Activity of Antibiotics against Burkholderia cepacia complex in Artificial Sputum Medium. bioRxiv [Preprint] 2023.12.13.571502. Available from: https://doi.org/10.1101/2023.12.13.571502
Salamzade R, Manson AL, Walker BJ, Brennan-Krohn T, Worby CJ, Ma P, He LL, Shea TP, Qu J, Chapman SB, Howe W, Young SK, Wurster JI, Delaney ML, Kanjilal S, Onderdonk AB, Bittencourt CE, Gussin GM, Kim D, Peterson EM, Ferraro MJ, Hooper DC, Shenoy ES, Cuomo CA, Cosimi LA, Huang SS, Kirby JE, Pierce VM, Bhattacharyya RP, Earl AM. Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance. Genome Med. 2022 Apr 5;14(1):37. doi: 10.1186/s13073-022-01040-y. PubMed PMID: 35379360; PubMed Central PMCID: PMC8981930.
Brennan-Krohn T, Grote A, Rodriguez S, Kirby JE, Earl AM. Transcriptomics Reveals How Minocycline-Colistin Synergy Overcomes Antibiotic Resistance in Multidrug-Resistant Klebsiella pneumoniae. Antimicrob Agents Chemother. 2022 Mar 15;66(3):e0196921. doi: 10.1128/aac.01969-21. Epub 2022 Jan 18. PubMed PMID: 35041511; PubMed Central PMCID: PMC8923212.
Brennan-Krohn T, Friar L, Ditelberg S, Kirby JE. Evaluation of the Synergistic Activity of Antibacterial and Antifungal Drugs against Candida auris Using an Inkjet Printer-Assisted Method. Antimicrob Agents Chemother. 2021 Sep 17;65(10):e0026821. doi: 10.1128/AAC.00268-21. Epub 2021 Jul 12. PubMed PMID: 34252295; PubMed Central PMCID: PMC8448112.
Brennan-Krohn T, Manetsch R, O'Doherty GA, Kirby JE. New strategies and structural considerations in development of therapeutics for carbapenem-resistant Enterobacteriaceae. Transl Res. 2020 Jun;220:14-32. doi: 10.1016/j.trsl.2020.02.008. Epub 2020 Mar 2. Review. PubMed PMID: 32201344; PubMed Central PMCID: PMC7293954.
Kirby JE, Brennan-Krohn T, Smith KP. Bringing Antimicrobial Susceptibility Testing for New Drugs into the Clinical Laboratory: Removing Obstacles in Our Fight against Multidrug-Resistant Pathogens. J Clin Microbiol. 2019 Dec;57(12). doi: 10.1128/JCM.01270-19. Print 2019 Dec. PubMed PMID: 31533983; PubMed Central PMCID: PMC6879291.
Brennan-Krohn T, Kirby JE. When One Drug Is Not Enough: Context, Methodology, and Future Prospects in Antibacterial Synergy Testing. Clin Lab Med.2019 Sep;39(3):345-358. doi: 10.1016/j.cll.2019.04.002. Epub 2019 Jun 12. Review. PubMed PMID: 31383261; PubMed Central PMCID: PMC6686866.
Brennan-Krohn T, Kirby JE. Synergistic Combinations and Repurposed Antibiotics Active against the Pandrug-Resistant Klebsiella pneumoniae Nevada Strain. Antimicrob Agents Chemother. 2019 Sep;63(9). doi: 10.1128/AAC.01374-19. Print 2019 Sep. PubMed PMID: 31307981; PubMed Central PMCID: PMC6709503.
Brennan-Krohn T, Kirby JE. Antimicrobial Synergy Testing by the Inkjet Printer-assisted Automated Checkerboard Array and the Manual Time-kill Method.J Vis Exp. 2019 Apr 18;(146). doi: 10.3791/58636. PubMed PMID: 31058886; PubMed Central PMCID: PMC6698365.
Brennan-Krohn T, Pironti A, Kirby JE. Synergistic Activity of Colistin-Containing Combinations against Colistin-Resistant Enterobacteriaceae. Antimicrob Agents Chemother. 2018 Oct;62(10). doi: 10.1128/AAC.00873-18. Print 2018 Oct. PubMed PMID: 30061285; PubMed Central PMCID: PMC6153801.
Truelson KA, Brennan-Krohn T, Smith KP, Kirby JE. Evaluation of apramycin activity against methicillin-resistant, methicillin-sensitive, and vancomycin-intermediate Staphylococcus aureus clinical isolates. Diagn Microbiol Infect Dis. 2018 Oct;92(2):168-171. doi: 10.1016/j.diagmicrobio.2018.05.018. Epub 2018 May 29. PubMed PMID: 29934071; PubMed Central PMCID: PMC6131043.
Brennan-Krohn T, Ozonoff A, Sandora TJ. Adherence to guidelines for testing and treatment of children with pharyngitis: a retrospective study. BMC Pediatr. 2018 Feb 9;18(1):43. doi: 10.1186/s12887-018-0988-z. PubMed PMID: 29426305; PubMed Central PMCID: PMC5807738.
Brennan-Krohn T, Yoon E, Nishino M, Kirby JE, Riedel S. Arthroconidia in lung tissue: an unusual histopathological finding in pulmonary coccidioidomycosis. Hum Pathol. 2018 Jan;71:55-59. doi: 10.1016/j.humpath.2017.07.013. Epub 2017 Aug 1. PubMed PMID: 28778515; PubMed Central PMCID: PMC5936468.
Smith KP, Richmond DL, Brennan-Krohn T, Elliott HL, Kirby JE. Development of MAST: A Microscopy-Based Antimicrobial Susceptibility Testing Platform.SLAS Technol. 2017 Dec;22(6):662-674. doi: 10.1177/2472630317727721. Epub 2017 Aug 24. PubMed PMID: 28837780; PubMed Central PMCID: PMC5744253.
Brennan-Krohn T, Truelson KA, Smith KP, Kirby JE. Screening for synergistic activity of antimicrobial combinations against carbapenem-resistant Enterobacteriaceae using inkjet printer-based technology. J Antimicrob Chemother. 2017 Oct 1;72(10):2775-2781. doi: 10.1093/jac/dkx241. PubMed PMID: 29091221; PubMed Central PMCID: PMC5890738.
Brennan-Krohn T, Smith KP, Kirby JE. The Poisoned Well: Enhancing the Predictive Value of Antimicrobial Susceptibility Testing in the Era of Multidrug Resistance. J Clin Microbiol. 2017 Aug;55(8):2304-2308. doi: 10.1128/JCM.00511-17. Epub 2017 May 3. PubMed PMID: 28468856; PubMed Central PMCID: PMC5527407.
Smith KP, Brennan-Krohn T, Weir S, Kirby JE. Improved Accuracy of Cefepime Susceptibility Testing for Extended-Spectrum-Beta-Lactamase-Producing Enterobacteriaceae with an On-Demand Digital Dispensing Method. J Clin Microbiol. 2017 Feb;55(2):470-478. doi: 10.1128/JCM.02128-16. Epub 2016 Nov 30. PubMed PMID: 27903600; PubMed Central PMCID: PMC5277516.